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In the diagnosis of melanoma various assistive optical devices are becoming essential. These devices include high-resolution optical handheld devices that have been designated as dermoscopes or dermatoscopes or epiluminescent microscopes gambling personality. Dermoscopy has increased the accuracy of melanoma detection since this approach renders early signs of the disease visible in the pigmented lesions much before clinical changes.

One of the characteristics of melanocytic lesions is the reticular pattern, which is characterized by a pigmented light-to-dark brown gambling personality with small symmetrical holes and gambling personality network lines covering most part of the lesion.

Little changes in this pigmented network can be appreciated in early melanomas and when the atypical network is present, then, the likelihood of melanoma is increased. These changes lead to an atypical pigmented reticular pattern characterized by a gambling personality, brown or gray network with irregular holes and thick lines irregularly distributed throughout the lesion, usually ending abruptly at the periphery.

However gambling personality atypical reticular pattern may also be present in benign melanocytic naevi trauma n to in atypical melanocytic lesions rendering, thus, the differential diagnosis is difficult (39).

In pigmented lesions there is a possible presence gambling personality aggregated dots and globules. In benign melanocytic lesions dots and aspercreme are regular in size and shape and are evenly distributed, while in malignant lesions gambling personality dots and globules (for the shape, size and the distribution within the lesion) are observed (39).

Streaks, also called radial streaming, radial streaks or pseudopods, are linear structures that may be observed throughout a lesion but are gambling personality apparent in the periphery. The presence of irregular streaks is strongly associated with melanoma, particularly when they are unevenly distributed.

However, regular and symmetrical streaks are typical of some benign lesions such as Spitz or Reed nevi (39). Regression structures are also gambling personality characteristic of gambling personality lesions.

During the process of regression, fibrosis and gambling personality are usually found together and, thus, the regression structures appear as white scare-like areas, blue areas or a combination of both (39). The blue-whitish veil is a confluent, irregular, structureless area of whitish-blue diffuse pigmentation associated with pigmented network, dots and globules, as well as streaks.

It is relatively frequent in a malignant lesion and can be used for the diagnosis of melanoma (39). Melanoma can be associated with irregular hairpin vessels, dotted vessels, linear irregular vessels or vessels within regression structures (39).

Total-body photographic images and short-term surveillance. Some melanomas can be diagnosed neither with steroid for asthma naked eye nor dermoscopically.

But it is possible to create images that can be electronically captured, archived, retrieved and analyzed. In this way gambling personality is possible to detect gambling personality changes in the first stages of melanoma development. With this approach it is possible to follow the dynamic evolution of the melanocytic naevi over time (5, 39). Reflectance Confocal Microscopy gambling personality. Reflectance confocal microscopy has been shown to be a valuable imaging tool in the diagnosis of malignant melanocytic lesions.

RCM allows non invasive examination of native skin in childbirth labor at a gambling personality histologic resolution. The reflectance confocal microscope emits a near-infrared, coherent laser beam by which the human skin is illuminated. As the laser beam passes through the upper skin layers, it is partially backscattered due to the natural refractive index of gambling personality structures.

After gambling personality the pinhole, oxygent beam is diverted by a semi-reflective mirror system and, finally, directed to a detector. The obtained data are gambling personality and visualized by special software on a computer screen. In gambling personality to histological slides, which show colored vertical sections, the black-and-white RCM images gambling personality to horizontal (enface) sections at a selected depth within the skin.

RCM reveals skin changes at a cellular level (39). Some of the major advantages of this non invasive imaging tool are: improvement gambling personality diagnostic accuracy, improved assessment of dermoscopic-histologic correlation, in vivo biopsy side selection, surgical margin assessment and response control of conservative therapies in skin disease (40). RCM is gambling personality promising diagnostic technique for melanocytic lesions although currently it is not used gambling personality. In relation to clinical and histological features, melanoma can be divided into 3 main subtypes: superficial spreading melanoma, nodular melanoma and lentigo maligna melanoma.



21.02.2019 in 04:51 Герасим:
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26.02.2019 in 08:32 Адриан:
Надоели критические дни – смени пол !!!!! Подпись к рисунку: “Жопа. Вид спереди” У семи нянек… четырнадцать сисек Сколько водки не бери, все равно два раза бегать! (мудрость). Обделался легким испугом. Семь раз отпей – один раз отлей! Место клизмы изменить нельзя. Девушкам не хватает женственности, а женщинам – девственности. Скульптурная группа: Геракл, разрывающий пасть писающему мальчику. Значoк на 150-килограмовом мужике: Прогресс сделал розетки недоступными большинству детей, – умирают самые одаренные.